MCL单分子成像RM21™...

MCL单分子成像RM21™显微镜平台

参考成交价格: 100~150万元[人民币]
技术特点

【技术特点】-- MCL单分子成像RM21™显微镜平台



Product Description

The RM21™ is designed as an adaptable microscopy platform which may be configured for a wide variety of microscopy techniques. The design approach to the RM21™ is unlike conventional optical microscopes. The RM21™ allows direct access to all of the optical pathway and has been engineered for precision alignment in all three axes. The RM21™ is compatible with 30mm and 60mm cage systems and is designed to be configured on a standard optical table. The RM21™ has been designed for stability and is nanopositioner ready. These attributes make the RM21™ an ideal platform for innovative instrument development and single molecule microscopy.

The RM21™ has three axes of precision motion. The objective lens holder (z-axis) is precision aligned with the optical axis of the platform and accomodates a single objective lens. The motorized lens positioner uses our proprietary intelligent control for low drift and high performance and has 50mm travel with 95nm step size. A fixed objective lens option is also available for maximum stability. Precision motion in X and Y can be achieved with manual XY micro-positioning (-MXY models) or automated XY micropositioning (-AXY models). All XY micropositioning stages travel 25mm per axis and are engineered for nanopositioning compatibility. The -AXY models employ our proprietary intelligent control. All automated axes may be ordered with optional optical encoders to provide displacement readouts.

The RM21™ is suitable for applications such as optical and magnetic tweezers, AFM integration and fluorescence microscopy. We offer a number of standard options including a TIRF Module that allows users to effortlessly shift between epifluorescence/TIRF/HILO microscopy techniques and a TIRF Lock™ to maintain the illumination angle. A wide range of customizations, such as increased ranges of motion, are also available. The RM21™ is nanopositioning ready and compatible with the Nano-Cyte® and Mad City Labs nanopositioners.

Highlights Three axes of precision motionFixed objective lens or automated objective lens positioning availablePrecision aligned three dimensional grid with over 200 tapped holesTIRF Module and TIRF Lock™ options availableAdjustable, precision aligned shelves and breadboardsCompatible with SM1/30mm & 60mm cage systemsPrecision manufactured base platforms for 45° prism mirror & SM1/30mm cage systemVibration damping feet with removable foot brackets

TIRF microscopy options

A typical application of the RM21™ microscope is single molecule fluorescence microscopy. A standard option available with the RM21™ is the TIRF Module, which provides simple adjustment of the TIR excitation beam to achieve epifluorescence or TIR illumination of the sample and all angles in between (HILO). The TIRF Module controls the angle of illumination and the focusing of the excitation beam onto the back focal plane of the objective lens. The TIRF Module is fully compatible with all models of the RM21™ and may be used in conjunction with Mad City Labs nanopositioning systems and the TIRF Lock™ option.

The TIRF Lock™ comprises a quadrant photodiode (QPD) head, electronic controller and LabVIEW based software. Once a user has set up TIR illumination and establishes a desired sample Z position, the TIRF Lock™ keeps the sample in the focal plane by measuring the displacement of the exiting TIRF beam and maintaining that position via software feedback control of the sample positioner. The TIRF Lock™ is fully compatible with Mad City Labs nanopositioning systems.

The RM21™ microscope when combined with the TIRF Module and TIRF Lock™ is an excellent instrument for single molecule microscopy offering versatility and stability.

Compatible Motion Control Software Packages:




RM21™ Models Available

All models available in imperial (-I) or metric (-M).
Supported lens threads: RMS, M25, M26, M27, M32
Side breadboards compatible with SM1/30mm/60mm cage systems

Nano-Cyte® compatible model
  • Model: RM21-NC-(thread)-I/M


  • Available options
  • 20nm optical encoders added to a specified axis

  • TIRF Module

  • TIRF Lock™

  • Top mount AFM Kit such as SPM-M Kit or custom configuration


  • Custom options
  • Fixed objective (-FZ). Please consult with our applications engineers prior to ordering.



Model ordering

RM21 model number explanation



Additional Information

RM21™ Catalog Pages



Drawing of RM21™



Drawing of RM21™-Metric

Related Products

  • TIRF Module

  • TIRF Lock

  • Nano-Cyte®

  • C-Focus™

  • Nano-View® Series

  • Nano-View®/M Series

  • MicroStage Series

  • Manual MicroStage-LT Series

  • Nano-F Series

  • Nano-OP Series High Speed Lens Positioners

  • Cyto-Lite™ Laser


【技术特点对用户带来的好处】-- MCL单分子成像RM21™显微镜平台


【典型应用举例】-- MCL单分子成像RM21™显微镜平台


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