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ASNS基因突变与药物因子介绍

2022.7.25
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zhaoqisun

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这个基因编码的蛋白质参与天冬酰胺的合成。这个基因补充了温度敏感型仓鼠突变体TS11的突变,该突变体在非耐受温度下阻止细胞周期G1期的进展。另外,还描述了该基因的剪接转录变体。
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.

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