该基因编码的蛋白是n-寡糖基转移酶(ost)复合物的催化亚单位,在内质网中起作用,将多糖链转移到目标蛋白的天冬酰胺残基上。还存在含有类似的催化亚基的独立的复合物,其具有重叠功能。已发现该基因编码不同亚型的多个转录变体。
The protein encoded by this gene is a catalytic subunit of the N-oligosaccharyltransferase (OST) complex, which functions in the endoplasmic reticulum to transfer glycan chains to asparagine residues of target proteins. A separate complex containing a similar catalytic subunit with an overlapping function also exists. Multiple transcript variants encoding different isoforms have been found for this gene.