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YAP1基因编码的功能和结构描述

2022.8.24
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zhaoqisun

致力于为分析测试行业奉献终身

这个基因编码河马信号通路的下游核效应器,它参与发育、生长、修复和体内平衡。已知该基因在多种癌症的发展和进展中发挥作用,作为该信号通路的转录调节因子,并可能作为癌症治疗的潜在靶点发挥作用。选择性剪接导致编码不同亚型的多个转录变体。

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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