ACVR1B antibody
Cat.#: 3455-1
Rabbit Monoclonal Antibody
Clone ID: EPR4815
Swiss Prot: P36896
Mol Weight: 52kDa
Size: 100ul
Description
ACVR1B is an activin A type IB receptor. Activins are dimeric growth and differentiation factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases, which include at least two type I and two type II receptors. ACVR1B is a type I receptor that is essential for signaling. Mutations in this protein are associated with pituitary tumors.
Recommended Applications
WB, IHC, ICC, FC
Applications and Recommended Dilution Factors
WB: 1:1,000-10,000
IHC: 1:500-1000
ICC: 1:100-250
FC: 1:100-500
Species Reactivity
Human, Mouse, Rat
Mouse cross reactivity tested by western blot and IHC
Rat cross reactivity tested by western blot only
Products Data
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Specificity
A synthetic peptide corresponding to residues in the extracellular domain of human ACVR1B was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ACVR1B antibody, ACTRIB antibody, ACVRLK4 antibody, ALK4 antibody, SKR2 antibody, Activin receptor type-1B antibody, Serine/threonine-protein kinase receptor R2 antibody
Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.