产品描述
20S Proteasome alpha1 antibody
Cat.#: S2317
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P25786
Mol Weight: 30.25kDa
Size: 100ug
Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Recommended Applications
WB, IHC, ICC
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
IHC: 1:100-1:500,IF:1:100-1:200
ICC: 1:100-1:200
Species Reactivity
Human
Other species have not been tested
Products Data
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Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 214 of 20S Proteasome alpha1
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
PSMA1 antibody, HC2 antibody, MGC14542 antibody, MGC14575 antibody, MGC14751 antibody, MGC1667 antibody, MGC21459 antibody, MGC22853 antibody, MGC23915 antibody, NU antibody, PROS30 antibody, Proteasome subunit alpha type-1 antibody, Macropain subunit C2 antibody, Multicatalytic endopeptidase complex subunit C2 antibody, Proteasome component C2 antibody, Proteasome nu chain antibody
