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BML-PW0585-0100 100 µl
BML-PW0585-0025 25 µl
Product Specification
Alternative Name: Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, Deubiquitinating enzyme 21, NEDD8-specific protease
Purity Detail: Purified by salt precipitation. 
Formulation: Liquid. In PBS containing 0.01% sodium azide.
Immunogen: Synthetic peptide corresponding to aa 60-74 of human USP21.
Source/Host: From rabbit.
Specificity: Recognizes human USP21.
Application: Western Blot (1:1'000)
Optimal conditions must be determined individually for each application.
Shipping: SHIPPED ON BLUE ICE
Short Term Storage: +4°C
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored at -20°C. Dilute with PBS, pH 7.2-7.4, containing 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used). Store diluted antibody at +4°C, do not freeze and use within 1 month.
Handling: After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.  
Miscellaneous/General: USP21 is a ubiquitin-specific protease that catalyzes the hydrolysis of ubH2A thereby acting to relieve ubH2A-specific repression. USP21 is also thought to be involved with hepatocyte regeneration. Furthermore, in addition to its deubiquitinylating activity, USP21 is capable of removing NEDD8 from NEDD8 conjugates but has no effect on SUMO conjugates.