产品描述
| 溶解性 | Soluble in DMSO (121 mg/ml), chloroform, water (<1 mg/ml), and ethanol (50 mM). |
| 存贮条件 | 储存温度2-8℃ |
| 产品介绍 | Fulvestrant是一种Estrogen receptor（ER）（雌激素受体）拮抗剂， IC50为0.094 nM。 |
| 备注 | Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.094 nM. |
| 生化机理 | ICI 182,780 is a high affinity estrogen receptor antagonist (IC50 = 0.29 nM), devoid of any partial agonism in vitro and ICI 182,780 is also a high affinity agonist at the membrane estrogen receptor, GPR30. |
| 别名 | 氟维司群;(7a,17b)-7-[9-(4,4,5,5,5-五氟戊亚磺酰基)壬烷基]-雌甾-1,3,5-(10)-三烯-3,17-二醇;Faslodex;ICI 182780;ZD 182780;ZD 9238;ZM 182780;(7a,17b)-7-[9-[(4,4,5,5,5pentafluoropentyl)Sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol |
