产品描述
| 熔点 | 180-183°C |
| 旋光率 | +221 to +226 deg(C=1, EtOH) |
| 溶解性 | Soluble in acetone, methanol, ethanol (10 mM), chloroform, and DMSO (100 mM). Insoluble in water. |
| 存贮条件 | 储存温度-20°C |
| 密度 | 1.2100 |
| 应用 | Corticosteroid is an activator of MCR. |
| 产品介绍 | Corticosterone, the major stress hormone, is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. |
| 生化机理 | Corticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membrane. Corticosterone induces apoptosis in murine bone marrow. |
| 别名 | 皮质酮;肾上腺酮;皮质甾酮;11β,21-Dihydroxy-4-pregnene-3,20-dione; 11β,21-Dihydroxyprogesterone; 4-Pregnene-11β,21-diol-3,20-dione; Kendall's Compound B; Reichstein's Substance H; |
