溶解性 | Soluble in water (< 1 mg/ml at 25 °C), chloroform, DMSO (100 mg/ml at 25 °C), methanol, and ethanol (< 1 mg/ml at 25 °C). |
存贮条件 | 储存温度-20°C |
应用 | A selective and competitive inhibitor of HMG-CoA reductase. |
产品介绍 | Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂, with IC50为11 nM。 |
备注 | Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM. |
生化机理 | Rosuvastatin Calcium Salt is a selective, competitive inhibitor of HMGCR (HMG-CoA reductase), that is also antilipemic. |
别名 | 瑞舒伐他汀钙; 罗舒伐他汀钙; 超级他汀钙; (3R,5S,6E)-7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰胺基)-5-嘧啶]-3,5-二羟基-6-庚烯酸钙;Rosuvastatin hemicalcium; ZD 4522 Calcium; Crestor;7-{4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid |