敏感性 | 对空气敏感 |
溶解性 | Soluble in DMSO: >10 mg/mL |
存贮条件 | 储存温度 -20°C,充氩保存 |
应用 | An L-type calcium channel protein inhibitor. |
产品介绍 | Azelnidipine是一种二氢吡啶类钙通道阻断剂。 |
备注 | Azelnidipine is a dihydropyridine calcium channel blocker. |
生化机理 | Azelnidipine is a novel dihydropyridine derivative, an L-type calcium channel protein inhibitor and an antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis. |
别名 | 阿折地平; 2-氨基-1,4-二氢-6-甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸3-[1-(二苯甲基)-3-氮杂啶] 5-异丙酯;CS 905; Calblock;2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl Ester ;3-[1-(Diphenylmethyl)-3-azetidinyl] 5-Isopropyl 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate |