溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
应用 | A series of AMPA modulators for the potential treatment of cognitive diseases |
产品介绍 | Ampalex (Ampakine CX516; CX516; BDP 12)是AMPA受体阳性变构调节剂,可作用于阿尔茨海默病,精神分裂等。 |
生化机理 | Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). IC50 value: Target: AMPA receptor Ampalex ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation. Researches suggest that AMPA receptors may be potential pharmaceutical targets for the treatment of neurodegenerative diseases, and highlights AMPAkines, in particular, as possible therapeutic agents. |
别名 | 安帕来斯;CX516; BDP 12; Ampakine CX516; 1-Piperidinyl-6-quinoxalinyl-methanone ; 6-(Piperidin-1-ylcarbonyl)quinoxaline |