产品描述
| 溶解性 |
|
| 存贮条件 | 储存温度2-8℃ |
| 产品介绍 | GW4064是一种farnesoid X receptor (FXR)激动剂，CV1细胞系中EC50为65 nM。浓度达到1 μM时，对其他核受体没有活性（ GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM in CV1 cell line and displays no activity at other nuclear receptors at concentrations up to 1 μM.） |
| 备注 | GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM. |
| 生化机理 |
GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).GW 4064 displays no activity at other nuclear receptors at concentrations up to 1 μM. GW 4064 improves hyperglycaemia and hyperlipidemia in diabetic db/db mice. |
| 别名 | ;3-(2,6-Dichlorophenyl)-4-(3’-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole |
