产品描述
| 熔点 | 81°C |
| 溶解性 | Soluble in acetone, ether, DMSO (15 mg/ml), DMF (30 mg/ml), ethanol (1 mg/ml), methanol (slightly soluble), benzene, chloroform, DMF:PBS (1:3 pH 7.2) (0.25 mg/ml), ethyl acetate, acetonitrile, and hexane. Insoluble in water. |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A hypolipidemic PPARα agonist. |
| 产品介绍 | Fenofibrate 是一种Fibrate类化合物，是纤维酸衍生物。 |
| 备注 | Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative. |
| 生化机理 | Fenofibrate is a hypolipidemic compound which acts as a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 18 μM for mouse and EC50 = 30 μM for human). Fenofibrate also binds to PPARγ with at least 10-fold less affinity, and is inactive at PPARδ at concentrations up to 100 μM. |
| 别名 | 非诺贝特; 2-甲基-2-(4-(4-氯苯甲酰基)苯氧基)丙酸异丙酯;2- [4-（4-氯苯甲酰）苯氧基]-2-甲基丙酸异丙酯; ;Procetofen; Trilipix;Sedufen;2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester;Isopropyl 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionate; |
