溶解性 | DMSO |
应用 | A pyridazinone derivative and a selective inhibitor of phosphodiesterase type III and IV |
产品介绍 | Zardaverine是新型的PDE3和4抑制剂,IC50分别为0.5 uM和0.8 uM。 |
生化机理 | Zardaverine is a pyridazinone derivative and a selective and dual inhibitor of PDE3 and PDE4. Zardaverine is a potent bronchiodilator in vitro. This compound has been shown to inhibit inflammatory cell function and exert a positive inotropic action on heart muscle. |
别名 | 6-[4-(二氟甲氧基)-3-甲氧基苯基]-3(2H)-哒嗪酮;6-(4-Difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone |