产品描述
| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 生化机理 |
ZM323881 is a potent and selective inhibitor of human vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) activity. ZM323881 selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC50 > 50 μM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM). |
| 别名 | ; |
