产品描述
| 溶解性 | Soluble in Dichloromethane, Methanol and Water. |
| 应用 | A selective facilitator of serotonin uptake. |
| 生化机理 | Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-H and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation counter. |
| 别名 | 噻奈普汀;硫耐扑定;噻耐普汀酸;dioxide; tianeptineacid; coaxil |
