产品描述
| 溶解性 | DMSO 100 mg/mL Ethanol 100 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Tofacitinib是高效JAK3抑制剂，IC50为1 nM，比对JAK2和JAK1的抑制性高20倍和100倍。 |
| 生化机理 |
Tasocitinib also known as CP690550 is an JAK kinase inhibitor. An IC50 estimated at 0.2 μM for PV patient progenitor cells. |
| 别名 | (3S,4S)-托法替尼;(3S,4S)-4-甲基-3-(甲基-7H-吡咯并[2,3-d]嘧啶-4-氨基)-beta-氧代-1-哌啶丙腈;(3S,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile |
