敏感性 | 对热敏感 |
溶解性 | Soluble in acetone, dimethyl formamide, methanol (slightly), and DMSO (10 mg/ml). Insoluble in water. |
存贮条件 | 储存温度-20°C |
应用 | A derivative of podophyllotoxin that has shown cytostatic effect & inhibition of topoisomerase II. |
产品介绍 | Teniposide 是一种化疗药物,主要用于治疗儿童急性淋巴细胞性白血病(ALL)。 |
备注 | Teniposide(Vumon)is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL). |
生化机理 | Teniposide is a glycoside-derivative of podophyllotoxin, has cytostatic effect. Teniposide inhibits Topo II(topoisomerase II)while induces apoptosis. |
别名 | 替尼泊甙;鬼臼噻吩甙; 4'-去甲基表鬼臼毒素-beta-D-噻吩亚甲基吡喃葡萄糖甙;Vumon; VM-26; VM26; VM 26;4′-Dimethyl-9-(4,6-O-2-thenyid)-epipodophyllotoxin; Tenoposide;[5R-[5alpha,5abeta,8aalpha,9beta(R*)]]-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienylmethylene)-beta-D-glucopyranosyl]oxy]-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one |