产品描述
| 溶解性 | Soluble in DMSO; Ethanol : ≥ 50 mg/mL (82.97 mM) |
| 存贮条件 | 储存温度-20°C |
| 应用 | Tipranavir is a nonpeptidic protease inhibitor and antiviral agent. |
| 产品介绍 | Tipranavir (PNU-140690) 有效抑制 HIV-1 蛋白酶 酶活性和二聚化，对抗多种蛋白酶抑制剂(PI)的HIV-1分离株具有有效的活性，IC50 为 66-410 nM。 |
| 生化机理 |
Tipranavir, a Nonpeptidic HIV protease inhibitor (NPPI), inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-PI-resistant HIV-1 isolates. Antiviral and Anti-HIV agents. |
| 别名 | 替拉那韦; N-[3-[(1R)-1-[(6R)-2-羟基-4-氧代-6-苯乙基-6-丙基-5H-吡喃-3-基]丙基]苯基]-5-(三氟甲基)吡啶-2-磺酰胺 ;PNU-140690;Aptivus;Tipranavir;N-[3-[(1R)-1-[(6R)-2-Hydroxy-4-oxo-6-phenethyl-6-propyl-5H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide |
