溶解性 | DMSO |
存贮条件 | 储存温度2-8°C |
产品介绍 | Olprinone(Loprinone)是磷酸二酯酶3(PDE3)抑制剂。 |
生化机理 | Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output after cardiopulmonary bypass (CPB). Olprinone was infused at a rate of 0.2 μg/kg/min when weaning from CPB was started. Olprinone has also shown potent antioxidative and anti-inflammatory effects in the meconium-induced oxidative lung injury. |
别名 | 奥普力农;罗普瑞酮;1,2-二氢-5-咪唑并[1,2-a]吡啶-6-基-6-甲基-2-氧代-3-吡啶甲腈;Loprinone;1,2-Dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile;5-(1,7-Diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-3-yl)-6-methyl-2-oxo-1H-pyridine-3-carbonitrile |