产品描述
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in water (89 mg/ml at 25 °C), 100% ethanol (slightly), methanol (slightly), and DMSO (89 mg/ml at 25 °C). Insoluble in acetone. |
| 存贮条件 | 储存温度-20°C |
| 应用 | Induces DNA damage by intercalating into DNA and inhibiting Topo II;It can be used to induce calreticulin surface expression in cells， as a genotoxin agent，as a topoisomerase inhibitor. |
| 产品介绍 | Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative. Induces DNA damage by intercalating into DNA and inhibiting Topo II (topoisomerase II). Mitoxantrone dihydrochloride induces interstrand DNA cross-links and DNA-protein cross-links in cellular systems. Mitoxantrone dihydrochloride has recently been shown to be an inhibitor of DNA methylation. |
| 备注 | Mitoxantrone HCl is a classic folic acid antagonist. |
| 别名 | 盐酸米托蒽醌;1,4-二羟基-5,8-双[[2-[(2-羟乙基)氨基]乙基]氨基]蒽-9,10-二酮二盐酸盐 盐酸米托蒽醌;1,4-二羟基-5,8-双[[2-[(2-羟乙基)氨基]乙基]氨基]蒽醌二盐酸盐 盐酸米托蒽醌;Novantrone dihydrochloride; 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride |
