溶解性 |
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存贮条件 | 储存温度-20°C |
备注 | Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hypertension (PAH). |
生化机理 |
Ambrisentan is an endothelin receptor type A-selective endothelin receptor antagonist. Ambrisentan is useful for pulmonary arterial hypertension (PAH). |