产品描述
| 熔点 | 194-198°C |
| 敏感性 | 对湿度敏感 |
| 溶解性 | Soluble in DMSO (40 mg/mL), ethanol (25 mg/mL warm), DMF (~7 mg/mL), PBS, PH 7.2 (~0.65 mg/mL), hot water, ethyl acetate, Chloroform Hexane, and methanol. |
| 存贮条件 | 密封保存。 |
| 密度 | 1.4780 |
| 应用 | An inhibitor of 5-LO and 12-LO. |
| 产品介绍 | Caffeic Acid is an endogenous phenolic phytochemical compound that exists in plants and many foods. A major metabolite product upon hydrolization of chlorogenic acid caffeic acid inhibits a number of lipoxygenases such as 5-LO (5-lipoxygenase), in a non-competitive manner, and 12-LO (12-lipoxygenase) inhibiting leukotriene synthesis resulting in further inhibition of immunoregulation. Caffeic Acid has also been shown to inhibit arachidonic acid metabolism in platelets at high doses. It has been observed to stimulate prostaglandin synthesis at high doses. Caffeic Acid is an inhibitor of GST, ODC, Tyk and Xanthine Oxidase. |
| 生化机理 | 检查： 1 、三氯化铁显色反应 符合规定 2 、应在323nm的波长处有最大吸收，在261nm的波长处有最小吸收。 符合规定 3 、本品的水溶液加盐酸及亚硝酸钠，再加氢氧化钠呈碱性，呈红色。 符合规定 |
| 别名 | 3,4-二羟基肉桂酸;3,4-二羟基苯丙烯酸;β-(3,4-二羟苯基)丙烯酸;3-(3,4-二羟苯基)-2-丙烯酸;3,4-二羥桂皮酸3-(3,4-Dihydroxyphenyl)-2-propenoic acid;3,4-Dihydroxycinnamic acid;3,4-Dihydroxybenzeneacrylic acid |
