Drug-Induced Liver Injury (DILI) Compound Library | MedChemExpress (MCE)
Drug Repurposing Compound Library Plus | MedChemExpress (MCE)
Drug Repurposing Compound Library | MedChemExpress (MCE)
Drug Metabolite Library | MedChemExpress (MCE)
Dopamine Receptor Compound Library | MedChemExpress (MCE)
Differentiation Inducing Compound Library | MedChemExpress (MCE)
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MCE 国际站:Cytoskeleton Compound Library
The cytoskeleton is responsible for contraction, cell motility, movement of organelles and vesicles through the cytoplasm, cytokinesis, intracellular signal transduction, and many other functions that are essential for cellular homeostasis and survival. It accomplishes these tasks through three basic structures: F-actin, microtubules, and intermediate filaments (IFs). The cytoskeleton is a dynamic structure where the three major filaments and tubules are under the influence of proteins that regulate their length, state of polymerization, and level of cross-linking. Since cytoskeleton is involved in virtually all cellular processes, cytoskeletal protein aberrations are the underlying reason for many pathological phenotypes, including several cardiovascular disease syndromes, neurodegeneration, cancer, liver cirrhosis, pulmonary fibrosis, and blistering skin diseases.MCE designs a unique collection of 1147 cytoskeleton-related compounds mainly focusing on the key targets in the cytoskeleton signal pathway and can be used in the research of cytoskeleton signal pathway and related diseases.
Description & Advantages:
• A unique collection of 1147 small molecules used for cytoskeleton research.
• Targets such as Kinesin, Microtubule/Tubulin, Arp2/3 Complex, Bcr-Abl, etc.
• Bioactivity and safety confirmed by preclinical research and clinical trials, some compounds have been approved by FDA.
• A useful tool to study cytoskeletal protein aberrations involved diseases such as cardiovascular disease, neurodegeneration, cancer, liver cirrhosis, etc.
• Structurally diverse, medicinally active, and cell permeable.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• NMR and HPLC validated to ensure high purity and quality.
• All compounds are in stock and continuously updated.
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• MCE (MedChemExpress) 拥有200 多种全球独家化合物库,我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物;
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• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;
• 产品的生物活性多经各国客户实验验证;
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;
• 专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;
• 与世界各大制药公司及知名科研机构建立了长期的合作。