将肿瘤细胞尾接种于裸鼠，通过观察裸鼠体内肿瘤的形成情况，从而评价出细胞的增殖能力；常用于肿瘤细胞全属性转移能力的检测。

技术原理

将肿瘤细胞通过尾静脉注射到动物体内，制备尾静脉接种转移模型，通过借助小动物活体成像仪器观察动物体内肿瘤转移灶的发生、发展情况，评价细胞在动物体内的转移能力，主要转移器官为肺脏，主要适用于肿瘤在动物肺部、肝部、全身性转移方向的研究。可提供的建模细胞系有：肝癌、肺癌、结肠癌、食管癌、胶质瘤等。

结果展示

肺癌细胞感染携带有Luc基因的慢病毒，尾静脉接种于4周龄裸小鼠，5周后活体成像，可见裸鼠体内有肿瘤形成

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