产品描述
| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | RG1678 (Bitopertin)是非竞争性甘氨酸重吸收（GlyT1）抑制剂。 |
| 生化机理 |
RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1). Recent Phase II data shows that RG1678 is effective in reducing the negative symptoms when given in combination with second generation antipsychotics. RG1678 is currently in Phase III trials for the treatment of the negative symptoms of schizophrenia. |
| 别名 | RG1678;RO4917838;RG-1678;RG 1678;RO-4917838;RO 4917838;比拓喷丁;(S)-[4-(3-氟-5-三氟甲基吡啶-2-基)哌嗪-1-基][5-(甲磺酰基)-2-(2,2,2-三氟-1-甲基乙氧基)苯基]甲酮;RG1678;RO4917838;RG-1678;RG 1678;RO-4917838;RO 4917838;Paliflutine;(S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone; [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone |
