溶解性 | water 100 mM |
存贮条件 | 充氩储存 |
产品介绍 | Pregabalin(CI-1008; PD-144723) is a GABA analogue and binds with high affinity and selectivity to the α2δ subunit of voltage-sensitive Ca2+ channels. Pregabalin(CI-1008; PD-144723) is a GABA analogue and binds with high affinity and selectivity to the α2δ subunit of voltage-sensitive Ca2+ channels and modulates their activity. IC50 value: Target: Ca2+ channel Pregabalin is an anticonvulsant, anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia. |
生化机理 | Pregabalin is a GABA analogue and binds with high affinity and selectivity to the α2δ subunit of voltage-sensitive Ca2+ channels and modulates their activity. Pregabalin is an anticonvulsant, anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia. |
别名 | CI-1008;PD-144723;(S)-Pregabalin;普瑞巴林;(3S)-3-氨甲基-5-甲基己酸;CI-1008;PD-144723;(S)-Pregabalin;3-(Aminomethyl)-5-methyl-hexanoic acid |