产品描述
| 熔点 | 148-150°C |
| 溶解性 | Soluble in Ethanol |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | A potent calcium channel protein inhibitor and blocker. |
| 产品介绍 | Nilvadipine是一种强效钙通道阻滞剂，IC50为0.03 nM。 |
| 备注 | Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. |
| 生化机理 | Nilvadipine is a potent calcium channel blocker that is used for treatment of hypertension. Nilvadipine, as other dihydropyridine calcium antagonists, decreases intracellular calcium concentration causing dilation of the coronary and systemic arteries. Nilvadipine acutely reduced brain Aβ levels in a transgenic mouse model of Alzheimer′s disease (AD). |
| 别名 | 5-异丙基-3-甲基-2-氰基-1,4-二氢-6-甲基-4-(3-硝基苯基)-3,5-吡啶二羧酸酯;2-氰基-1,4-二氢-6-甲基-4-(3-硝基苯基)-3,5-吡啶二羧酸-5-异丙基-3-甲酯;3-甲氧羰基-6-甲基-4-(3-硝基苯基)-2-氰基-1,4-二氢吡啶-5-羧酸异丙;2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 5-Isopropyl 3-Methyl Ester;5-Isopropyl 3-Methyl 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate;FK235; Escor; FR34235; Nivadil; Nivadip |
