熔点 | 165.0 - 169.0℃ |
溶解性 |
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应用 | Used in the treatment of non-insulin dependent diabetes mellitus (NIDDM). |
产品介绍 | Gliclazide 是一种全细胞β细胞ATP敏感的钾离子电流抑制剂,IC50为184 ?à 30 nM。 |
备注 | Gliclazide (Diamicron) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 ± 30 nM. |
生化机理 | Gliclazide is a sulfonylurea hypoglycemic agent used as an antidiabetic. |
别名 | 格列齐特; 甲磺双环脲; 1-(3-氮杂双环[3,3,0]辛基)-3-对甲苯磺酰脲;1-[3-Azabicyclo[3.3.0]oct-3-yl]-3-p-toluenesulfonylurea |